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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKH
All Species:
7.27
Human Site:
Y656
Identified Species:
20
UniProt:
Q86XP1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP1
NP_690874.2
1220
134866
Y656
P
A
N
Q
S
S
D
Y
D
S
T
E
T
D
E
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
Y656
P
A
N
Q
S
S
D
Y
D
S
T
E
T
D
E
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
S605
E
G
F
V
L
G
L
S
E
S
E
E
K
M
D
Dog
Lupus familis
XP_534133
1182
132580
N618
P
V
N
Q
S
F
D
N
D
S
T
E
T
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
D689
G
I
Q
S
P
P
I
D
D
S
K
E
A
D
E
Chicken
Gallus gallus
XP_001232791
1333
149344
K768
Q
S
P
V
E
Y
S
K
E
L
D
E
S
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108193
586
65385
K81
V
R
A
T
N
N
C
K
W
T
T
L
A
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
T1131
P
E
H
E
Q
T
P
T
N
K
G
A
N
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
A581
A
I
T
S
A
T
T
A
T
T
Q
G
P
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
62.2
90.7
N.A.
N.A.
N.A.
N.A.
82.3
76.8
N.A.
39
N.A.
34.9
N.A.
N.A.
51.5
Protein Similarity:
100
99.8
73.4
92.8
N.A.
N.A.
N.A.
N.A.
88.1
82.9
N.A.
43.2
N.A.
46.5
N.A.
N.A.
64.1
P-Site Identity:
100
100
13.3
80
N.A.
N.A.
N.A.
N.A.
33.3
13.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
80
N.A.
N.A.
N.A.
N.A.
33.3
33.3
N.A.
26.6
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
12
0
12
0
0
12
0
0
0
12
23
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
34
12
45
0
12
0
0
45
12
% D
% Glu:
12
12
0
12
12
0
0
0
23
0
12
67
0
0
56
% E
% Phe:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
0
12
0
0
0
0
12
12
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
0
0
0
0
12
0
0
0
0
0
0
12
12
% I
% Lys:
0
0
0
0
0
0
0
23
0
12
12
0
12
12
12
% K
% Leu:
0
0
0
0
12
0
12
0
0
12
0
12
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
34
0
12
12
0
12
12
0
0
0
12
0
0
% N
% Pro:
45
0
12
0
12
12
12
0
0
0
0
0
12
0
0
% P
% Gln:
12
0
12
34
12
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
23
34
23
12
12
0
56
0
0
12
12
0
% S
% Thr:
0
0
12
12
0
23
12
12
12
23
45
0
34
0
0
% T
% Val:
12
12
0
23
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _